Butyrylcholinesterase Expression in Plants

Archived

DARPA - Defense Sciences Office

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Description

DARPA is seeking innovative research proposals that will demonstrate the ability to produce a recombinant butyrylcholinesterase (rBuChE) using the Nicotiana benthamiana plant-based expression platform that has the same pharmacokinetic profile as a plasma-derived human butyrylcholinesterase (hBuChE) butyrylcholinesterase. The funding is intended to establish the technical precedence for the use of the plant platform to generate a rapid and scalable form of pre-exposure therapeutic bioscavenger against organophosphate nerve agents. Funding is for basic research only. The anticipated period of funding is for 12 months.

Who can apply

  • Unrestricted

Contact

BAA Coordinator
DARPA-BAA-12-31@darpa.mil

Key dates & funding
  • PostedFeb 16, 2012
  • ClosesMay 17, 2012
  • CFDA12.910
Categories
Science and Technology and other Research and Development

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