Targeting Persistent HIV Reservoirs (TaPHIR) (R21/R33)

Archived

National Institutes of Health

Description

The purpose of this FOA is to stimulate the development of innovative tools and strategies for curing HIV infection. HIV establishes latent infection in long-lived cells that form a reservoir of virus that persists in infected individuals even after years of treatment with highly active antiretroviral therapy (HAART). Curing HIV infection requires innovative strategies to identify and eliminate these reservoir cells. The task is especially difficult given the lack of HIV protein expression during latency and the low frequency of latently infected cells during treatment. Novel approaches are therefore sought to efficiently monitor and specifically target reservoirs of latently infected cells to facilitate the testing of strategies to cure HIV infection in vivo.

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV

Key dates & funding
  • PostedFeb 17, 2012
  • ClosesApr 25, 2014
  • CFDA93.242, 93.855, 93.856
Categories

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