National Institutes of Health

Description

HIV+ alcohol users remain an underserved group at high risk for medication non-adherence and rapid disease progression, medication toxicities, organ failure, and poor viremic control leading to increased risk of transmission and premature death. It has been estimated that the effective implementation of alcohol interventions for HIV+ individuals may reduce the rates of new infections by nearly 20% and extend life by up to 15 years in some at-risk and patient populations respectively. This new initiative seeks to advance knowledge of the effective implementation and comparative effectiveness of alcohol-focused interventions among HIV+ individuals. Multiple factors need to be investigated, including potentially important patient and provider characteristics, and the organizational, financial, and structural factors that facilitate or inhibit the delivery of evidence-based services for HIV+ individuals with a range of alcohol use disorders. The overall goal is to inform clinical decision-making that will enhance treatment outcomes and reduce harms associated with interventions for HIV+ individuals with alcohol use disorders. This solicitation is divided into two parts, one or both of which an applicant may choose to address. These parts include: 1) comparative effectiveness research focused on understanding factors related to patient engagement in appropriate alcohol and HIV care and retention in treatment; and 2) modeling and testing alternative approaches to the implementation of effective interventions to reduce HIV disease transmission and progression. This announcement addresses the need to further develop patient- centered approaches for making informed health care decisions and to improve research on health care delivery and outcomes.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV