Food and Drug Administration

Description

The purpose of this study is to investigate in vitro-in vivo correlations of parenteral microspheres. The encapsulated agent may be a small molecule or peptide, and the dosage form should be an injectable. An in vitro dissolution test which correlates with in vivo absorption should be investigated. In vivo studies should be conducted in a suitable animal model.The results from this project will help to understand the release mechanisms of microspheres and how in vitro studies could be used to predict in vivo bioavailability.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

Jennerfer Torres-Hernandez <br/>Grants Management Specialist <br/>Phone 301-827-9607
Jennerfer.Torres-Hernandez@fda.hhs.gov