Susceptibility and Variability in Human Response to Chemical Exposure

Archived

Environmental Protection Agency

Description

The U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is seeking applications proposing research to study life stage and/or genetic susceptibility in order to better characterize the sources of human variability in response to chemical exposure. The adverse outcome pathways (AOP) concept has the potential to serve as a framework for using susceptibility indicators, biomonitoring, and high throughput screening (HTS) data in an integrated manner to predict population responses to novel, potentially harmful, chemicals. While much emphasis has been placed on improved biomonitoring and HTS approaches, research is needed to understand the underlying factors that influence human susceptibility and to develop tools and methods for the identification and use of susceptibility indicators in this context. This solicitation provides the opportunity for the submission of applications for projects that may involve human subjects research.

Who can apply

  • Others

Contact

Mitch Lasat, Phone: 703-347-8099
lasat.mitch.@epa.gov

Key dates & funding
  • PostedJun 10, 2013
  • ClosesSep 24, 2013
  • Award floor$0
  • Award ceiling$800,000
  • Program funding$2,600,000
  • Expected awards4
  • CFDA66.509
Categories

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