National Institutes of Health

Description

The purpose of this funding opportunity announcement (FOA) is to invite applications to participate in a new NHLBI Pulmonary Vascular Disease Phenomics Program (hereafter referred to as "PVDOMICS"). Teams of investigators will perform comprehensive, deep phenotyping across the current World Health Organization (WHO)-classified pulmonary hypertension (PH) clinical Groups 1 through 5 (http://www.nhlbi.nih.gov/health/health-topics/topics/pah/types.html), which will lead to novel subclassifications of patients with pulmonary vascular-right ventricular disease, based on molecular and radiographic as well as clinical characteristics, which can be associated with specific molecular mechanisms of pathogenesis. This research is intended to lead to identification of both endophenotypes of lung vascular disease and biomarkers of disease that may be useful for early diagnosis or for assessment of interventions to prevent or treat this condition. This FOA solicits applications for the Data Coordinating Center (DCC) and runs in parallel with a separate FOA that solicits applications for the Clinical Centers (CCs) (RFA HL-14-027). The common phenotyping protocol will be aimed at:

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV