National Institutes of Health

Description

The purpose of this FOA is to invite pilot/feasibility (R03) projects on: 1) descriptive studies to identify putative juvenile protective factors, 2) experimental studies to test hypotheses about their effects on aging and 3) translational studies to explore the potential risks and benefits of maintaining or modulating the level of juvenile protective factors in adult life. Juvenile protective factors are physiological factors that maintain or enhance certain functions across all or some stages of post-natal maturation, but which diminish or disappear during transitions between developmental stages (e.g., infancy, adiposity rebound, adrenarche, puberty, growth cessation). This FOA is uniquely focused on studies which involve comparisons between post-natal developmental stages or pre- vs. post-maturational changes to identify potential juvenile protective factors and their effects on aging. Pilot studies in in vitro models, in laboratory animals or in humans may be proposed.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV