National Institutes of Health

Description

The purpose of the Caenorhabditis Interventions Testing Program (CITP) is to test, under standardized conditions at a consortium of three sites, potential intervention strategies which may decelerate the rate of aging in genetically diverse species and strains of Caenorhabditis. All three laboratories in the CITP use identical standard operating procedures to test the same compounds (interventions) at the same concentrations and under the same conditions. The CITP will continue to use life span as its primary outcome for an intervention on a currently defined set of Caenorhabditis species and strains. This FOA calls for renewal and expansion of the scientific scope of the CITP with the following goals: 1. Continue to test compounds for effects on lifespan; 2. Increase the number of strains examined in lifespan studies as described in RFA AG-13-010. 3. Incorporate a limited set of studies for health span on selected compounds; 4. Incorporate studies to establish optimal effective doses when an initial test indicates the compound may be robust for its effect on lifespan across numerous strains of Caenorhabditis.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

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