National Institutes of Health

Description

The purpose of this Funding Opportunity Announcement (FOA) is to develop a comprehensive understanding of innate and adaptive immune responses triggered by pathogens, adjuvants, or vaccines using a systems biology approach. The basis of the research program will be to conduct forward genetic screens of mutant or genetically diverse mice, combined with systems level analysis, to identify previously unappreciated key immune regulatory genes, signaling pathways, or mechanisms; and will include validation of these pathways in human cells and tissues. The long-range goal of this program is to advance our understanding of immune response dynamics following infection with a pathogen or administration of an adjuvant or vaccine; and to provide foundational information that can be applied to the development of novel translational approaches for production of vaccines or immune-based therapeutics.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV