Phenotypic and Functional Characterization of ApoE2 to Inform Translation Strategies for Aging-Related Conditions (R21)

Archived

National Institutes of Health

Description

The purpose of this FOA is to support exploratory and developmental new research activities on ApoE2 and other variants to improve understanding of physiologic and cellular differences attributable to the ApoE e2 allele (vs. other ApoE alleles), and how they mediate ApoE e2s differential effects on longevity and risk for age-related conditions. This will aid in the identification of potential therapeutic targets for interventions that prevent or ameliorate aging-related diseases by mimicking favorable differential effects of the ApoE e2 variant, while avoiding adverse effects.

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV

Key dates & funding
  • PostedJul 15, 2016
  • ClosesSep 7, 2019
  • Award ceiling$200,000
  • CFDA93.866
Categories

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