National Institutes of Health

Description

This Funding Opportunity Announcement (FOA) requests applications for the Kidney Precision Medicine Project (KPMP) Recruitment Sites (RS) to recruit participants with either acute kidney injury (AKI) or chronic kidney disease (CKD) into longitudinal cohort studies. The RS will collaborate with the KPMP Tissue Interrogation Sites and Central Hub to obtain and evaluate kidney biopsies from participants, create a kidney tissue atlas, define disease subgroups, and identify critical cells, pathways and targets for novel therapies. Applicants should propose to study either AKI or CKD, outline initial cohorts of interest, provide inclusion/exclusion criteria, and estimate recruitment targets given the FOA budget and KPMP objectives. Applicants should have documented experience with patient recruitment and safely obtaining kidney biopsies for clinical and/or research purposes. The initial UG3 exploratory phase will be used to demonstrate that the site can recruit and follow a sufficient number of well-characterized participants with either AKI or CKD, and safely obtain high-quality research kidney biopsies while conforming to the highest ethical, research and clinical standards. UG3 projects that have met their milestones will be administratively considered by the NIDDK and prioritized for transition to the UH3 implementation phase. UH3 awards will support continued recruitment into larger cohort studies. Applicants to this FOA must address both the UG3 and UH3 phases. This FOA is intended to support only human studies and applications that include animal or model systems are not responsive.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV