National Institutes of Health

Description

The primary objective of the work to be supported by this funding opportunity is to understand the mechanisms by which female sex hormones and sex hormone-based therapies can increase the risk of venous and arterial thromboembolism in pre-menopausal women. Understanding the basic physiopathology of how sex hormones may induce or add to the pre-existing risk of thrombosis will strengthen our understanding of the mechanisms underlying thrombus formation in relevant clinical situations such as peripartum or in women using contraceptives or undergoing in vitro fertilization. Such research may help identify women at higher thrombotic risk and thus help guide their clinical care. It could also lead to the identification of potential new therapeutics to prevent thrombus formation. The FOA purpose does not include research on thromboembolism related comorbidities in post-menopausal women.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV