Implementation Research to Improve Case Finding, Cascade Screening, and Treatment for Familial Hypercholesterolemia (FH) (R61/R33 Clinical Trial Required)

Archived

National Institutes of Health

Description

This milestone-driven Funding Opportunity Announcement (FOA) invites applications for single-site clinical trials that: (1) address barriers that impede population-level implementation of case finding and cascade screening (i.e., blood relatives of FH index cases are systematically contacted based on their risk according to the pattern of inheritance); (2) explore implementation science methodologies to assess the uptake, cost-effectiveness, feasibility, and scalability of family-based cascade screening programs for familial hypercholesterolemia (FH); (3) develop or improve machine learning algorithms and data mining techniques to find high-risk individuals using electronic health records (EHRs); and (4) optimize treatment strategies and health outcomes.

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV
FBOWebmaster@OD.NIH.GOV

Key dates & funding
  • PostedApr 16, 2020
  • ClosesMay 7, 2021
  • CFDA93.233, 93.837, 93.838, 93.839, 93.840
Categories

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