National Institutes of Health

Description

The TBEL program aims to integrate basic and translational cancer research concepts to examine the direct causal relationships and interactions of an early lesion, its microenvironment, and host-systemic factors as co-organizers of tumor initiation (or suppression) and malignant progression. The ultimate goals of the TBEL program are to further understand the biological and pathophysiological mechanisms driving or restraining precancers and early cancers and facilitate biology-backed precision prevention approaches. The responsibilities of the CDMC will be to (1) coordinate consortium-wide meetings and conferences, and cross-consortium collaborative activities; (2) provide statistical and computational analysis support; and (3) establish program data hub for data capture, curation and management, and protocol development and registration. The other scientific unit of the TBEL program will comprise the U54 Centers, which will be structured to efficiently bridge gaps between basic and translational research on early lesions and their microenvironments. This Notice is being provided to allow potential applicants sufficient time to develop a responsive TBEL Coordinating and Data Management Center application. The FOA is expected to be published in May 2021 with an anticipated application due date in October 2021. Details of the planned pre-application webinar will be announced in the Guide after publication of the FOA. The companion notice for the TBEL U54 Centers is: NOT-CA-21-XXX. The FOA will not be restricted to specific early lesion/cancer type(s).

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>OERWebmaster03@od.nih.gov
OERWebmaster03@od.nih.gov