Development and Validation of Harmonized Methodologies to Measure NAD+ and Related Metabolites in Clinical Trials (U01 Clinical Trial Required)

Archived

National Institutes of Health

Description

This Notice of Funding Opportunity (NOFO) invites applications to develop and validate the standardized protocols for measuring nicotinamide adenine dinucleotide (NAD+) and related metabolites levels in humans, including sample collection and storage, assays calibration, and standardization of measurements across different types of samples such as plasma, tissue, or serum extracts, and validation of these protocols. Limited preclinical animal studies could be proposed by the applicants, if such studies are integral part of the applications and if they are needed to test the select elements of the standardized protocols in animal models before such protocols could be tested in humans. The proposed studies will be funded by individual awards, but the awardees will be required to interact as a network to exchange information, discuss their progress, pitfalls and issues arising during studies implementation.

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others

Contact

NIH Grants Information<br/>grantsinfo@nih.gov
grantsinfo@nih.gov

Key dates & funding
  • PostedJul 5, 2023
  • ClosesNov 2, 2023
  • CFDA93.866
Categories

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