Understanding the mechanisms underlying the age-related changes in gait biomechanics and the impact on the increased metabolic cost of walking (R01 Clinical Trial Optional)
ArchivedNational Institutes of Health
Description
The National Institute on Aging (NIA)invitesR01applicationsthat proposehuman studiesto better understand the mechanisms underlying compensatory gait, posture and molecular changes that contribute to slower walking speed and increased metabolic cost of walking. This Notice of Funding Opportunity (NOFO) encourages interdisciplinary collaborations to design integrative approaches that explore interactions among multiple systems (e.g., skeletal, muscle, tendon, somatosensory and central nervous). This NOFO also encourages innovative approaches such as computational modeling, imaging and sensor technologies, machine learning and artificial intelligence to disentangle compensatory gait alterations with aging that contribute to increased metabolic cost of walking and fatigue. Areas of interest include: 1) mechanisms and effects of central nervous system changes; 2) neuromuscular changes; 3) skeletal muscle bioenergetics 4) computational modeling and simulation; and5) changes in tissue structure and function (e.g., muscle-tendon complex, extracellular matrix).
Who can apply
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal governments (Federally recognized)
- Public housing authorities / Indian housing authorities
- Native American tribal organizations (other than Federally recognized)
- Nonprofits with 501(c)(3) status (other than higher education)
- Nonprofits without 501(c)(3) status (other than higher education)
- Private institutions of higher education
- For-profit organizations other than small businesses
- Small businesses
- Others
Contact
NIH Grants Information<br/>grantsinfo@nih.gov
grantsinfo@nih.gov
- PostedAug 26, 2024
- ClosesNov 7, 2024
- Award ceiling$500,000
- CFDA93.866
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