Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances

Forecasted

National Institutes of Health

Description

The National Institute on Drug Abuse (NIDA) seeks to advance its mission by supporting the expansion of the Collaboratory on Neural Ensembles & Used Substances (NExUS), an effort to build a knowledgebase of the neural cell populations and computations altered by substance-associated experiences, and underlying neurobehavioral states characteristic of addiction, or protective against it. This notice is provided to allow prospective applicants to develop applications that achieve the following goals:1) Collect and share granular datasets descriptive of neural cell populations tuned to tractable features of substance-related experiences2) Integrate cell-resolved readouts of ensemble activity with other granular data modalities (e.g., molecular cell identity, epigenetic state, morphology, spatial localization or connectivity)3) Develop tools for analysis and visualization of ensemble composition and geometry, and document their scalability4) Inform and test models for the mechanisms whereby cells or motifs are recruited into coding ensembles5) Enable synergies among NExUS-funded projects and with other cell atlasing efforts through coordination of outreach, data standards, analytics, common spatial frameworks, and reference taxonomiesGrant Authorities that allow NIDA to forecast this opportunity are as follows: Section 301 (42 U.S.C. § 241) and Section 405 (42 U.S.C. § 284).

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others

Contact


INBranch_NIDA@nih.gov

Key dates & funding
  • PostedSep 11, 2025
  • Award ceiling$700,000
  • Expected awards4
  • CFDA93.279
Categories

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