INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)

Posted

National Institutes of Health

Description

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

Who can apply

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and State controlled institutions of higher education
  • Native American tribal governments (Federally recognized)
  • Public housing authorities / Indian housing authorities
  • Native American tribal organizations (other than Federally recognized)
  • Nonprofits with 501(c)(3) status (other than higher education)
  • Nonprofits without 501(c)(3) status (other than higher education)
  • Private institutions of higher education
  • For-profit organizations other than small businesses
  • Small businesses
  • Others

Contact

The INCLUDE Project<br/>DownSyndromeINCLUDE@mail.nih.gov
DownSyndromeINCLUDE@mail.nih.gov

Key dates & funding
  • PostedMay 12, 2026
  • ClosesJun 15, 2028
  • Award ceiling$500,000
  • Program funding$3,000,000
  • Expected awards4
  • CFDA93.121, 93.173, 93.233, 93.242, 93.310, 93.350, 93.351, 93.395, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.855, 93.865, 93.866, 93.867, 93.879
Categories

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