National Institutes of Health

Description

Purpose.This Funding Opportunity Announcement (FOA), issued by the National Institute of Mental Health (NIMH), solicits Exploratory/Developmental Phased Innovation (R21/R33) grant applications from institutions or organizations that propose to generate and characterize induced pluripotent stem (iPS) cells from human control and/or patient populations with cognitive, affective, social, sleep and developmental brain disorders. This can, but does not need to, include disorders in which a genetic linkage has already been inferred. Applications that combine expertise in stem cell biology, cortical development and the clinical study or treatment of mental disorders are strongly encouraged. Responsive applications will place an emphasis on appropriate validation of iPS cells and their derivatives, evaluating the hetero/homogeneity of any cell populations to be screened and use of cellular assays relevant to brain function and mental disorders. Studies involving the acquisition of tissue from new subjects should include provisions to archive and distribute non-induced (e.g., primary) cells. Since studies likely require several areas of expertise, applicants are encouraged to include multiple PIs on the application.

Who can apply

• Public and State controlled institutions of higher education
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV