National Institutes of Health

Description

-Purpose. This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), solicits innovative research project (R01) grant applications to enhance mechanistic understanding of the dynamic interrelationship between bioactive food components and/or food combinations and cancer prevention. Projects proposed in response to this FOA must focus on either multiple dietary bioactive components, intact foods, and/or multiple foods utilizing physiologically relevant concentrations of the bioactive agents. The objective is to investigate the impact of dietary components on complex cellular and molecular networks to better understand the basis for the multifaceted interactions of food components in cancer prevention. Proposed projects should apply new high-throughput genomic, epigenomic, proteomic, and metabolomic technologies to either evaluate multiple molecular targets within a cancer process or multiple processes. The main outcome of these studies must be the prioritization of targets/processes that are most relevant to cancer prevention by dietary components. The overall long-term goal is to use such information in developing dietary strategies to reduce cancer risk and/or modify tumor behavior. -Mechanism of Support. This FOA will utilize the NIH R01 grant mechanism. -Investigators not having sufficient preliminary data may consider submitting an application to Cancer Prevention Research Small Grants Program that uses the R03 funding mechanism and has broader scientific scope (http://grants.nih.gov/grants/guide/pa-files/PAR-06-313.html).

Who can apply

• Public and State controlled institutions of higher education
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster <br/>FBOWebmaster@OD.NIH.GOV <br/>
FBOWebmaster@OD.NIH.GOV