National Institutes of Health

Description

Purpose. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) of the National Institutes of Health solicit Research Project Grant (R01) applications for human studies to develop a highly reliable, easy to operate system linking continuous glucose monitoring to insulin delivery in a closed loop system.The goal is to address barriers that limit progress toward a closed loop system and specifically to 1) address behavioral factors that limit use of these systems, 2) use the technologies as tools to advance understanding of the pathophysiology of glucose regulation in patients with type 1 diabetes and 3) test and improve the safety, reliability and utility of these technologies in humans. Research goals include improved metabolic control with decreased glycemic excursions, increased lifestyle flexibility and improved quality of life in patients with diabetes. Only human studies will be considered responsive to this FOA.

Who can apply

• State governments
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV