National Institutes of Health

Description

Purpose. This funding opportunity announcement (FOA) solicits cooperative agreement applications for Biomarker Reference Laboratories (BRLs), one of the four components of the Early Detection Research Network (EDRN). EDRN is a national consortium funded to discover, develop, and validate biomarkers for early cancer detection, risk assessment and molecular diagnosis and prognosis of early cancer. The BRLs serve as a Network resource for clinical and laboratory validation of biomarkers, including technological developments and assay refinement. The other three main components of the EDRN are: the Biomarker Developmental Laboratories (BDLs), which have the responsibility for the development and characterization of new, or the refinement of existing, biomarkers and biomarker assays, the Clinical Validation Centers (CVCs), which conduct clinical research on the validation of biomarkers in early cancer detection and risk assessment and serve as resource centers for the EDRN by participating in collaborative biomarker validation studies and collaborating with EDRN BDLs and BRLs; and the Data Management and Coordinating Center (DMCC), which supports statistical and computational analyses, informatics infrastructure, and the coordination of network-wide meetings and conferences. Mechanism of Support. This FOA utilizes the NIH Cooperative Agreement (U24) award mechanism. Parallel FOAs for other EDRN components include RFA-CA-09-017 (U01) for BDLs, RFA-CA-09-018 (U01) for CVCs, and RFA-CA-09-020 (U24) for DMCC.

Who can apply

• Public and State controlled institutions of higher education
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV