National Institutes of Health

Description

Purpose. The National Institute of Allergy and Infectious Diseases (NIAID) invites new or renewal applications from single institutions or consortia of institutions to participate in a cooperative interdisciplinary research program for large-scale, broad-scope genomic studies in clinical transplantation of solid organ, tissue, and cells. The goals of this program are to identify and characterize gene polymorphisms and gene expression patterns that: (1) correlate with and/or predict transplantation outcomes; (2) define immune responses relating to the onset and severity of acute and chronic graft rejection; (3) predict responses to immunosuppression to allow tailoring of therapy; and (4) elucidate the genetic basis of variability in graft survival between populations or individuals. The long-term goal of the program is to understand the genetic basis of immune-mediated graft rejection and differences in transplant outcomes to provide a rational basis for developing more effective treatments to improve long-term graft survival and provide a better quality-of-life for transplant patients. Mechanism of Support. This Funding Opportunity Announcement (FOA) will utilize the single project (U01), and multi-project (U19) Cooperative Agreement award mechanism. Funds Available and Anticipated Number of Awards. The NIAID anticipates that approximately $4 million total costs will be available in FY 2011 to fund two to four new or renewal U01 and/or U19 awards.

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State controlled institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities / Indian housing authorities
• Native American tribal organizations (other than Federally recognized)
• Nonprofits with 501(c)(3) status (other than higher education)
• Nonprofits without 501(c)(3) status (other than higher education)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Contact

NIH OER Webmaster<br/>FBOWebmaster@OD.NIH.GOV<br/>
FBOWebmaster@OD.NIH.GOV